And the winner is…

All of us. Thanks to James Allison and Tasuku Honjo, winners of the 2018 Nobel Prize in Medicine, we now have a much better understanding of cancer, and how to treat it. Allison and Honjo characterized two very important and potent pathways – called “immune checkpoints” – that can shut down the immune response (CTLA-4 and PD-1). Anyone heard of “monoclonal antibodies?” Of course you have, and well, that’s thanks to these two smart people. For a really good article on their discovery and what it has led to go here. Dr. Allison is currently working at MD Anderson and you can see a short video of him here. MD Anderson has a very nice 3-minute video on “What is immunotherapy” that is worth a watch. Everyone together now, say “thanks guys”