This week, researchers from MD Anderson reported “significant durable disease control seen in patients with lung and thyroid cancers harboring the RET oncogene.” This is great news for people with the RET alteration. RET is linked to half of all medullary thyroid cancers, 20% of papillary thyroid cancers and 1-2% of non-small cell lung cancers. The phase I study of the compound BLU-667 from Blueprint Medicines is being conducted with 84 patients. According to lead investigator Vivek Subbiah “the data show the precision targeted therapy with next-generation kinase inhibitors can have a powerful impact for patients with RET-driven cancers.” All this seems great, unless you own Blueprint stock, which dropped 9% on the news. Wall Street. Anyway, here’s hoping the drug will show continued durability and effectiveness. You’re my boy blue!