Which would be worse, your doctor demands you change your eating habits or prescribes a medication that increases your risk of stroke? For those still resisting lifestyle changes in favor of drugs, tune in to this: a popular category of heartburn medications called proton pump inhibitors (PPIs) has been linked to a 21% greater risk of stroke. A study of 245,000 patients who had an endoscopy showed that within 6 years of follow-up, 9,500 patients had their first ischemic stroke. Researchers controlled for other risk factors, investigated their medications and found patients on the highest dose of PPIs had a stroke risk from 30% for lansoprazole to 94% for pantoprazole. Add that to PPIs’ links to dementia and heart attacks and then reconsider fatty foods and large portion sizes.