MedCity, in southeast London, is a collaboration between the mayor and the capital’s three academic health science centers – Imperial College Academic Health Science Centre, King’s Health Partners, and UCL Partners – and it just might be the future of healthcare. Significant changes to an industry typically come from the outside. The Dollar Shave Club was not started by Gillette, Uber was not a spin-off from a taxi company, and Kim Kardashian was…you get the point. MedCity is a collaboration, not a disruption. It is meeting in the middle and tackling clinical trial recruitment, bench research, market access, workspace/equipment, and fundraising/investment opportunities. The three most important words in healthcare might be: location, location, location.