1. Gene therapy for Alzheimer’s disease

While still a long way from the finish line, gene therapy looks promising for blocking the onset of Alzheimer’s disease. Researchers at Imperial College London injected lentivirus, which contains the PGC-1-alpha gene, into the hippocampus and the cortex of mice susceptible to the development of Alzheimer’s disease. Compared to a control group of similarly susceptible mice, the treated group showed little development of amyloid plaques. Not to get too technical here but amyloid plaque is stuff believed to lead to bad things. Like strokes in golf, you want fewer of them. Treated mice also showed no loss of brain cells in the hippocampus and normal performance on memory tasks. All together now… Sci-ence!, Sci-ence!, Sci-ence! Well done, smart people.